منابع مشابه
Glucosamine.
Glucosamine is one of the most popular dietary supplements sold in the United States. Most clinical trials have focused on its use in osteoarthritis of the knee. The reported adverse effects have been relatively well studied and are generally uncommon and minor. No significant supplement-drug interactions involving glucosamine have been reported. The National Institutes of Health-sponsored Gluc...
متن کاملGlucosamine Metabolism
Recent studies in this laboratory, concerned with hexosamine metabolism, required Gm-6-P,’ Galm-BP, and their respective N-acetyl derivatives. Several methods are available for the preparation of Cm-6-P, but there appears to be no previous report of Calm-6-P, although an acid-stable Galm-P has been isolated from cartilage (4). Earlier reports indicated that hexokinase and ATP would phosphorylat...
متن کاملUDP-glucosamine as a substrate for dolichyl monophosphate glucosamine synthesis.
The sugar nucleotide analogue UDP-glucosamine was found to function as a sugar donor in microsomal preparations of both chick-embryo cells and rat liver, yielding dolichyl monophosphate glucosamine (Dol-P-GlcN). This was characterized by t.l.c. and retention by DEAE-cellulose. Glucosamine was the only water-soluble product released on mild acid hydrolysis. Dol-P-GlcN did not serve as substrate ...
متن کاملGlucosamine metabolism. V. Enzymatic synthesis of glucosamine 6-phosphate.
Studies in viva on the biosynthesis of n-glucosamine, with the use of specifically labeled glucose in the rat (1,2) and in group A streptococci (3-5) showed that the glucose carbon chain was preserved during its conversion to the hexosamine. Leloir and Cardini (6, 7) noted that extracts obtained from Neurospora crassa converted glutamine and hexose phosphate to glutamic acid and a product tenta...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2006
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(07)60452-x